PPP1R1A Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases. Belongs to the protein phosphatase inhibitor 1 family. Note: This description may include information from UniProtKB.
Protein type: Inhibitor; Protein phosphatase, regulatory subunit
Cellular Component: 
Reference #:  P01099 (UniProtKB)
Alt. Names/Synonyms: I-1; IPP-1; IPP1; PPP1R1A; PPR1A; Protein phosphatase 1 regulatory subunit 1A; Protein phosphatase inhibitor 1
Gene Symbols: PPP1R1A
Molecular weight: 18,032 Da
Basal Isoelectric point: 5.48  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB