PTPRA iso2 Belongs to the protein-tyrosine phosphatase family. Receptor class 4 subfamily. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: EC 3.1.3.48; Membrane protein, integral; Motility/polarity/chemotaxis; Receptor protein phosphatase, tyrosine
Chromosomal Location of Human Ortholog: 20p13
Cellular Component:  integral component of plasma membrane; integral component of synaptic membrane; plasma membrane; receptor complex; Schaffer collateral - CA1 synapse
Molecular Function:  protein binding; protein tyrosine phosphatase activity; transmembrane receptor protein tyrosine phosphatase activity
Biological Process:  axon guidance; insulin receptor signaling pathway; MAPK cascade; modulation of chemical synaptic transmission; peptidyl-tyrosine dephosphorylation
Reference #:  P18433-2 (UniProtKB)
Alt. Names/Synonyms: HEPTP; HLPR; HPTPA; HPTPalpha; Leukocyte common antigen-related peptide (protein tyrosine phosphate); LRP; protein tyrosine phosphatase, receptor type, A; protein tyrosine phosphatase, receptor type, alpha polypeptide; Protein-tyrosine phosphatase alpha; PTPase-alpha; PTPLCA-related phosphatase; PTPRA; PTPRL2; R-PTP-alpha; Receptor-type tyrosine-protein phosphatase alpha; RPTPA; tyrosine phosphatase alpha
Gene Symbols: PTPRA
Molecular weight: 89,630 Da
Basal Isoelectric point: 6.47  Predict pI for various phosphorylation states
Select Structure to View Below

PTPRA iso2

Protein Structure Not Found.


Cross-references to other databases:  cBioPortal  |  Wikipedia  |  Pfam  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene