|
PTPRA
Belongs to the protein-tyrosine phosphatase family. Receptor class 4 subfamily. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
|
| Protein type: EC 3.1.3.48; Membrane protein, integral; Motility/polarity/chemotaxis; Receptor protein phosphatase, tyrosine |
| Chromosomal Location of rat Ortholog: 3q36 |
|
Cellular Component:
focal adhesion; intracellular membrane-bounded organelle; membrane; plasma membrane; receptor complex; Schaffer collateral - CA1 synapse; synaptic membrane
|
|
Molecular Function:
protein binding; protein tyrosine phosphatase activity; protein-containing complex binding
|
|
Biological Process:
insulin receptor signaling pathway; integrin-mediated signaling pathway; modulation of chemical synaptic transmission; oligodendrocyte differentiation; positive regulation of oligodendrocyte differentiation; protein dephosphorylation; protein phosphorylation; regulation of focal adhesion assembly
|
|
Reference #:
Q03348
(UniProtKB)
|
|
Alt. Names/Synonyms: Lrp; MGC93561; protein tyrosine phosphatase alpha; protein tyrosine phosphatase, receptor type, A; Protein-tyrosine phosphatase alpha; Ptpra; R-PTP-alpha; Receptor-type tyrosine-protein phosphatase alpha
|
|
Gene Symbols: Ptpra
|
|
Molecular weight:
90,260 Da
|
|
Basal Isoelectric point:
6.21
Predict pI for various phosphorylation states
|
