PTPRA Belongs to the protein-tyrosine phosphatase family. Receptor class 4 subfamily. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: EC; Membrane protein, integral; Motility/polarity/chemotaxis; Receptor protein phosphatase, tyrosine
Chromosomal Location of rat Ortholog: 3q36
Cellular Component:  focal adhesion; intracellular membrane-bounded organelle; membrane; plasma membrane; receptor complex; Schaffer collateral - CA1 synapse; synaptic membrane
Molecular Function:  protein binding; protein tyrosine phosphatase activity; protein-containing complex binding
Biological Process:  insulin receptor signaling pathway; integrin-mediated signaling pathway; modulation of chemical synaptic transmission; oligodendrocyte differentiation; positive regulation of oligodendrocyte differentiation; protein dephosphorylation; protein phosphorylation; regulation of focal adhesion assembly
Reference #:  Q03348 (UniProtKB)
Alt. Names/Synonyms: Lrp; MGC93561; protein tyrosine phosphatase alpha; protein tyrosine phosphatase, receptor type, A; Protein-tyrosine phosphatase alpha; Ptpra; R-PTP-alpha; Receptor-type tyrosine-protein phosphatase alpha
Gene Symbols: Ptpra
Molecular weight: 90,260 Da
Basal Isoelectric point: 6.21  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  Reactome  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene