CK1A2 Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily. Note: This description may include information from UniProtKB.
Protein type: CK1 group; CK1 family; CK1-A subfamily; EC; Kinase, protein; Protein kinase, CK1; Protein kinase, Ser/Thr (non-receptor)
Chromosomal Location of human Ortholog: 13q13.3
Cellular Component:  cytoplasm; cytosol; nucleus
Molecular Function:  ATP binding; protein serine kinase activity; protein serine/threonine kinase activity
Biological Process:  negative regulation of canonical Wnt signaling pathway; peptidyl-serine phosphorylation; signal transduction; Wnt signaling pathway
Reference #:  Q8N752 (UniProtKB)
Alt. Names/Synonyms: casein kinase 1 alpha 1 like; casein kinase 1, alpha 1-like; casein kinase I alpha S-like; Casein kinase I isoform alpha-like; CK1; CK1A2; CKI-alpha-like; CSNK1A1L; KC1AL; MGC33182
Gene Symbols: CSNK1A1L
Molecular weight: 39,086 Da
Basal Isoelectric point: 9.48  Predict pI for various phosphorylation states
CST Pathways:  Hedgehog Signaling
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  KinBase  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein