CK1G3 Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Regulates fast synaptic transmission mediated by glutamate. Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily. 6 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: CK1 group; CK1 family; EC 2.7.11.1; Kinase, protein; Protein kinase, CK1; Protein kinase, Ser/Thr (non-receptor)
Chromosomal Location of Human Ortholog: 18q11
Cellular Component:  cytoplasm; nucleus; plasma membrane
Molecular Function:  ATP binding; protein serine/threonine kinase activity
Biological Process:  endocytosis; peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; positive regulation of canonical Wnt signaling pathway; protein autophosphorylation; protein phosphorylation; Wnt signaling pathway
Reference #:  Q62763 (UniProtKB)
Alt. Names/Synonyms: casein kinase 1, gamma 3; Casein kinase I isoform gamma-3; CK1G3; CKI-gamma 3; Csnk1g3; KC1G3
Gene Symbols: Csnk1g3
Molecular weight: 51,429 Da
Basal Isoelectric point: 9.24  Predict pI for various phosphorylation states
CST Pathways:  Hedgehog Signaling  |  Wnt/ß-Catenin Signaling
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CK1G3

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene