syndecan-2 a heparan sulfate proteoglycan type I membrane protein that belongs to the syndecan proteoglycan family. Preferentially expressed in cells of mesenchymal origin. Is tyrosine phosphorylated and forms a complex with EphB2 in mouse brain. Plays a role in mediating adhesion and proliferation of colon carcinoma cells. Note: This description may include information from UniProtKB.
Protein type: Cell adhesion; Cell surface; Membrane protein, integral; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 7q22
Cellular Component:  cell surface; integral component of membrane; neuronal cell body; plasma membrane; synapse
Molecular Function:  identical protein binding; PDZ domain binding; protein binding
Biological Process:  cell migration; dendrite morphogenesis; regulation of dendrite morphogenesis; response to caffeine; response to hypoxia; wound healing
Reference #:  P34900 (UniProtKB)
Alt. Names/Synonyms: Fibroglycan; Heparan sulfate proteoglycan core protein; HSPG; Hspg1; Ryudocan/syndecan 2; Sdc2; SYND2; syndecan 2; Syndecan-2
Gene Symbols: Sdc2
Molecular weight: 22,149 Da
Basal Isoelectric point: 4.52  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene