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TXNDC12
Possesses significant protein thiol-disulfide oxidase activity. Widely expressed. Note: This description may include information from UniProtKB.
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| Protein type: EC 1.8.4.2; Endoplasmic reticulum; Other Amino Acids Metabolism - glutathione; Oxidoreductase; Secreted; Secreted, signal peptide |
| Chromosomal Location of human Ortholog: 1p32.3 |
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Cellular Component:
endoplasmic reticulum; endoplasmic reticulum lumen
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Molecular Function:
protein binding; protein-disulfide reductase (glutathione) activity; protein-disulfide reductase activity
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Biological Process:
negative regulation of cell death; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
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Reference #:
O95881
(UniProtKB)
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Alt. Names/Synonyms: AG1; AGR1; anterior gradient homolog 1; endoplasmic reticulum protein ERp19; Endoplasmic reticulum resident protein 18; Endoplasmic reticulum resident protein 19; endoplasmic reticulum thioredoxin superfamily member, 18 kDa; ER protein 18; ER protein 19; ERP16; ERp18; ERp19; hAG-1; hTLP19; PDIA16; protein disulfide isomerase family A, member 16; thioredoxin domain containing 12; thioredoxin domain containing 12 (endoplasmic reticulum); Thioredoxin domain-containing protein 12; Thioredoxin-like protein p19; TLP19; TXD12; TXNDC12
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Gene Symbols: TXNDC12
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Molecular weight:
19,206 Da
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Basal Isoelectric point:
5.25
Predict pI for various phosphorylation states
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