TXNDC12 Possesses significant protein thiol-disulfide oxidase activity. Widely expressed. Note: This description may include information from UniProtKB.
Protein type: EC; Endoplasmic reticulum; Other Amino Acids Metabolism - glutathione; Oxidoreductase; Secreted; Secreted, signal peptide
Chromosomal Location of human Ortholog: 1p32.3
Cellular Component:  endoplasmic reticulum; endoplasmic reticulum lumen
Molecular Function:  protein binding; protein-disulfide reductase (glutathione) activity; protein-disulfide reductase activity
Biological Process:  negative regulation of cell death; negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
Reference #:  O95881 (UniProtKB)
Alt. Names/Synonyms: AG1; AGR1; anterior gradient homolog 1; endoplasmic reticulum protein ERp19; Endoplasmic reticulum resident protein 18; Endoplasmic reticulum resident protein 19; endoplasmic reticulum thioredoxin superfamily member, 18 kDa; ER protein 18; ER protein 19; ERP16; ERp18; ERp19; hAG-1; hTLP19; PDIA16; protein disulfide isomerase family A, member 16; thioredoxin domain containing 12; thioredoxin domain containing 12 (endoplasmic reticulum); Thioredoxin domain-containing protein 12; Thioredoxin-like protein p19; TLP19; TXD12; TXNDC12
Gene Symbols: TXNDC12
Molecular weight: 19,206 Da
Basal Isoelectric point: 5.25  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  ENZYME  |  Phospho3D  |  Phospho.ELM  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene