CRYGB a major structural protein of the eye lens. A member of the beta/gamma-crystallin family. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. Gamma-crystallins are involved in cataract formation. Note: This description may include information from UniProtKB.
Protein type: Cytoskeletal
Chromosomal Location of Human Ortholog: 2q33.3
Cellular Component:  cytoplasm; nucleus
Molecular Function:  structural constituent of eye lens
Biological Process:  lens fiber cell morphogenesis; visual perception
Disease: Cataract 39, Multiple Types
Reference #:  P07316 (UniProtKB)
Alt. Names/Synonyms: CRGB; CRYG2; CRYGB; crystallin, gamma 1-2; crystallin, gamma B; Gamma-B-crystallin; Gamma-crystallin 1-2; Gamma-crystallin B
Gene Symbols: CRYGB
Molecular weight: 20,908 Da
Basal Isoelectric point: 6.88  Predict pI for various phosphorylation states
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CRYGB

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene