RNF167 May act as an E3 ubiquitin-protein ligase, or as part of the E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, such as UBE2E1, and then transfers it to substrates, such as SLC22A18. May play a role in growth regulation involved in G1/S transition. Strongly expressed in the kidney and liver (at protein level). Note: This description may include information from UniProtKB.
Protein type: EC 6.3.2.-; EC; Ligase; Membrane protein, integral; Ubiquitin conjugating system; Ubiquitin ligase
Chromosomal Location of Human Ortholog: 17p13.2
Cellular Component:  cytoplasm; endomembrane system; integral component of membrane
Molecular Function:  protein binding; ubiquitin-protein transferase activity; zinc ion binding
Biological Process:  negative regulation of cell cycle; protein polyubiquitination
Reference #:  Q9H6Y7 (UniProtKB)
Alt. Names/Synonyms: 5730408C10Rik; DKFZp566H073; E3 ubiquitin-protein ligase RNF167; LP2254; RING finger protein 167; RING-type E3 ubiquitin transferase RNF167; RING105; RN167; RNF167
Gene Symbols: RNF167
Molecular weight: 38,299 Da
Basal Isoelectric point: 5.37  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB