MTIF3
IF-3 binds to the 28S ribosomal subunit and shifts the equilibrum between 55S ribosomes and their 39S and 28S subunits in favor of the free subunits, thus enhancing the availability of 28S subunits on which protein synthesis initiation begins. Belongs to the IF-3 family. Note: This description may include information from UniProtKB.
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Protein type: Mitochondrial; Translation; Translation initiation |
Chromosomal Location of human Ortholog: 13q12.2 |
Cellular Component:
mitochondrion
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Molecular Function:
protein binding; ribosomal small subunit binding; ribosome binding; translation factor activity, RNA binding; translation initiation factor activity
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Biological Process:
mitochondrial translational initiation; ribosome disassembly
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Reference #:
Q9H2K0
(UniProtKB)
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Alt. Names/Synonyms: FLJ33676; IF-3(Mt); IF-3Mt; IF3(mt); IF3M; IF3mt; mitochondrial translational initiation factor 3; MTIF3; Translation initiation factor IF-3, mitochondrial
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Gene Symbols: MTIF3
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Molecular weight:
31,725 Da
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Basal Isoelectric point:
9.7
Predict pI for various phosphorylation states
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