MTIF3 IF-3 binds to the 28S ribosomal subunit and shifts the equilibrum between 55S ribosomes and their 39S and 28S subunits in favor of the free subunits, thus enhancing the availability of 28S subunits on which protein synthesis initiation begins. Belongs to the IF-3 family. Note: This description may include information from UniProtKB.
Protein type: Mitochondrial; Translation; Translation initiation
Chromosomal Location of human Ortholog: 13q12.2
Cellular Component:  mitochondrion
Molecular Function:  protein binding; ribosomal small subunit binding; ribosome binding; translation factor activity, RNA binding; translation initiation factor activity
Biological Process:  mitochondrial translational initiation; ribosome disassembly
Reference #:  Q9H2K0 (UniProtKB)
Alt. Names/Synonyms: FLJ33676; IF-3(Mt); IF-3Mt; IF3(mt); IF3M; IF3mt; mitochondrial translational initiation factor 3; MTIF3; Translation initiation factor IF-3, mitochondrial
Gene Symbols: MTIF3
Molecular weight: 31,725 Da
Basal Isoelectric point: 9.7  Predict pI for various phosphorylation states
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MTIF3

Protein Structure Not Found.


Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho.ELM  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB  |  Ensembl Protein