TMEM38A Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores. Belongs to the TMEM38 family. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 19p13.11
Cellular Component:  integral component of membrane; nuclear membrane; sarcoplasmic reticulum membrane
Molecular Function:  potassium channel activity
Biological Process:  cellular response to caffeine; endoplasmic reticulum organization; potassium ion transmembrane transport; protein homotrimerization; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion; release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
Reference #:  Q9H6F2 (UniProtKB)
Alt. Names/Synonyms: MGC3169; TM38A; TMEM38A; Transmembrane protein 38A; TRIC-A; TRICA; Trimeric intracellular cation channel type A
Gene Symbols: TMEM38A
Molecular weight: 33,260 Da
Basal Isoelectric point: 8.56  Predict pI for various phosphorylation states
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Protein Structure Not Found.

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