CRYBA1 a major structural protein of the eye lens. A member of the beta/gamma-crystallin family. Defects are the cause of congenital zonular cataract with sutural opacities. Two splice-variant isoforms have been described. Note: This description may include information from UniProtKB.
Chromosomal Location of mouse Ortholog: 11 B5|11 46.74 cM
Cellular Component: 
Molecular Function:  identical protein binding; structural constituent of eye lens
Biological Process:  camera-type eye development; lens development in camera-type eye; negative regulation of cytokine production; negative regulation of ERK1 and ERK2 cascade; negative regulation of phosphatidylinositol 3-kinase signaling; negative regulation of protein kinase B signaling; negative regulation of TOR signaling; phagocytosis; positive regulation of anoikis; regulation of autophagy; visual perception
Reference #:  P02525 (UniProtKB)
Alt. Names/Synonyms: BA3/; BA3/A1; Beta-A1-crystallin; beta-A3/A1-crystallin; Beta-crystallin A1; CRBA1; Cry; Cryb; Cryba1; crystallin, beta A1; MGC130310; OTTMUSP00000008544
Gene Symbols: Cryba1
Molecular weight: 23,401 Da
Basal Isoelectric point: 5.96  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene