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SIAT1
Transfers sialic acid from CMP-sialic acid to galactose-containing acceptor substrates. Belongs to the glycosyltransferase 29 family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: EC 2.4.99.1; Glycan Metabolism - N-glycan biosynthesis; Membrane protein, integral; Transferase |
| Chromosomal Location of mouse Ortholog: 16 B1|16 14.03 cM |
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Cellular Component:
extracellular region; Golgi apparatus; Golgi medial cisterna; Golgi membrane; Golgi trans cisterna; membrane
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Molecular Function:
beta-galactoside alpha-2,6-sialyltransferase activity; glycosyltransferase activity; protein homodimerization activity; sialyltransferase activity; transferase activity
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Biological Process:
N-acetylneuraminate metabolic process; negative regulation of chemotaxis; negative regulation of macrophage apoptotic process; positive regulation of mononuclear cell proliferation; protein glycosylation; protein N-linked glycosylation via asparagine; protein sialylation; regulation of substrate adhesion-dependent cell spreading; sialylation
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Reference #:
Q64685
(UniProtKB)
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Alt. Names/Synonyms: Alpha 2,6-ST 1; AW742324; beta galactoside alpha 2,6 sialyltransferase 1; Beta-galactoside alpha-2,6-sialyltransferase 1; CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1; MGC116663; OTTMUSP00000031674; OTTMUSP00000032134; Sialyltransferase 1; Siat1; St6G; St6gal; ST6Gal I; St6Gal-I; St6gal1; ST6GalI
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Gene Symbols: St6gal1
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Molecular weight:
46,586 Da
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Basal Isoelectric point:
9.01
Predict pI for various phosphorylation states
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