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SIAT1
Transfers sialic acid from CMP-sialic acid to galactose-containing acceptor substrates. Belongs to the glycosyltransferase 29 family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: EC 2.4.99.1; Glycan Metabolism - N-glycan biosynthesis; Membrane protein, integral; Transferase |
| Chromosomal Location of human Ortholog: 3q27.3 |
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Cellular Component:
extracellular region; Golgi cisterna membrane; Golgi membrane; integral component of membrane
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Molecular Function:
beta-galactoside alpha-2,6-sialyltransferase activity; protein binding; protein homodimerization activity; sialyltransferase activity
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Biological Process:
humoral immune response; N-acetylneuraminate metabolic process; O-glycan processing; protein N-linked glycosylation via asparagine; sialylation
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Reference #:
P15907
(UniProtKB)
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Alt. Names/Synonyms: Alpha 2,6-ST 1; B-cell antigen CD75; Beta-galactoside alpha-2,6-sialyltransferase 1; CMP-N-acetylneuraminate beta-galactosamide alpha-2,6-sialyltransferase; CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1; MGC48859; Sialyltransferase 1; sialyltransferase 1 (beta-galactoside alpha-2,6-sialyltransferase); SIAT1; ST6 beta-galactosamide alpha-2,6-sialyltranferase 1; ST6 beta-galactoside alpha-2,6-sialyltransferase 1; ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1; ST6Gal I; ST6GAL1; ST6GalI; ST6N
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Gene Symbols: ST6GAL1
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Molecular weight:
46,605 Da
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Basal Isoelectric point:
9.13
Predict pI for various phosphorylation states
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