P2RY11 Receptor for ATP and ADP coupled to G-proteins that activate both phosphatidylinositol-calcium and adenylyl cyclase second messenger systems. Not activated by UTP or UDP. Belongs to the G-protein coupled receptor 1 family. Highest expression in liver and spleen. Note: This description may include information from UniProtKB.
Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Chromosomal Location of human Ortholog: 19p13.2
Cellular Component:  plasma membrane
Molecular Function:  G protein-coupled ATP receptor activity; neurotransmitter receptor activity; signaling receptor activity
Biological Process:  activation of adenylate cyclase activity; calcium-mediated signaling; cellular response to ATP; defense response; G protein-coupled purinergic nucleotide receptor signaling pathway; G protein-coupled receptor signaling pathway; neuronal signal transduction; phospholipase C-activating G protein-coupled receptor signaling pathway
Reference #:  Q96G91 (UniProtKB)
Alt. Names/Synonyms: P2RY11; P2Y purinoceptor 11; P2Y11; P2Y11 receptor; purinergic receptor P2Y, G-protein coupled, 11; purinergic receptor P2Y11
Gene Symbols: P2RY11
Molecular weight: 40,345 Da
Basal Isoelectric point: 9.35  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene