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P2RY11
Receptor for ATP and ADP coupled to G-proteins that activate both phosphatidylinositol-calcium and adenylyl cyclase second messenger systems. Not activated by UTP or UDP. Belongs to the G-protein coupled receptor 1 family. Highest expression in liver and spleen. Note: This description may include information from UniProtKB.
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| Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR |
| Chromosomal Location of human Ortholog: 19p13.2 |
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Cellular Component:
plasma membrane
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Molecular Function:
G protein-coupled ATP receptor activity; neurotransmitter receptor activity; signaling receptor activity
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Biological Process:
activation of adenylate cyclase activity; calcium-mediated signaling; cellular response to ATP; defense response; G protein-coupled purinergic nucleotide receptor signaling pathway; G protein-coupled receptor signaling pathway; neuronal signal transduction; phospholipase C-activating G protein-coupled receptor signaling pathway
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Reference #:
Q96G91
(UniProtKB)
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Alt. Names/Synonyms: P2RY11; P2Y purinoceptor 11; P2Y11; P2Y11 receptor; purinergic receptor P2Y, G-protein coupled, 11; purinergic receptor P2Y11
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Gene Symbols: P2RY11
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Molecular weight:
40,345 Da
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Basal Isoelectric point:
9.35
Predict pI for various phosphorylation states
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