ARHGAP5 GTPase-activating protein for Rho family members. Detected in skin fibroblasts (at protein level) (PubMed:8537347). 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: GAP; GAP, Rac/Rho; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 12 C1|12 22.16 cM
Cellular Component:  cytoplasm; cytosol; endoplasmic reticulum; membrane; plasma membrane
Molecular Function:  GTP binding; GTPase activator activity; GTPase activity; SH2 domain binding
Biological Process:  mammary gland development; positive regulation of cell migration; positive regulation of mesenchymal cell proliferation; regulation of cell size; signal transduction
Reference #:  P97393 (UniProtKB)
Alt. Names/Synonyms: Arhgap5; p190; p190-; p190-B; p190B; RHG05; Rho GTPase activating protein 5; Rho GTPase-activating protein 5; Rho-type GTPase-activating protein 5; Rhogap5
Gene Symbols: Arhgap5
Molecular weight: 172,113 Da
Basal Isoelectric point: 5.93  Predict pI for various phosphorylation states
CST Pathways:  Adherens Junction Dynamics
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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ARHGAP5

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene