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ARHGAP5
GTPase-activating protein for Rho family members. Detected in skin fibroblasts (at protein level) (PubMed:8537347). 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: GAP; GAP, Rac/Rho; Motility/polarity/chemotaxis |
| Chromosomal Location of mouse Ortholog: 12 C1|12 22.16 cM |
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Cellular Component:
cytoplasm; cytosol; endoplasmic reticulum; membrane; plasma membrane
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Molecular Function:
GTP binding; GTPase activator activity; GTPase activity; SH2 domain binding
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Biological Process:
cell migration; epithelial cell migration; mammary gland development; positive regulation of epithelial cell migration; positive regulation of mesenchymal cell proliferation; regulation of cell size; Rho protein signal transduction; signal transduction
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Reference #:
P97393
(UniProtKB)
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Alt. Names/Synonyms: Arhgap5; p190; p190-; p190-B; p190B; RHG05; Rho GTPase activating protein 5; Rho GTPase-activating protein 5; Rho-type GTPase-activating protein 5; Rhogap5
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Gene Symbols: Arhgap5
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Molecular weight:
172,472 Da
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Basal Isoelectric point:
6.11
Predict pI for various phosphorylation states
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CST Pathways:
Adherens Junction Dynamics
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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