H2B Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Belongs to the histone H2B family. Note: This description may include information from UniProtKB.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: (6p21.3)
Cellular Component: 
Reference #:  HSBO22 (GenPept)
Alt. Names/Synonyms: H2B; H2B 291A; H2B-F; H2B.1; H2B/f; H2B1B; H2B1F; H2BFF; histone cluster 1, H2bb; Histone H2B.f
Gene Symbols: H2BC3
Molecular weight: 13,775 Da
Basal Isoelectric point: 10.32  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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H2B

Protein Structure Not Found.


Cross-references to other databases:  GeneCards  |  Entrez-Gene  |  GenPept