FOXN3 Acts as a transcriptional repressor. May be involved in DNA damage-inducible cell cycle arrests (checkpoints). 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: DNA-binding; Transcription factor
Chromosomal Location of rat Ortholog: 6q32
Cellular Component:  nucleus
Molecular Function:  DNA-binding transcription factor activity; protein C-terminus binding; sequence-specific DNA binding
Biological Process:  craniofacial suture morphogenesis; mitotic G2 DNA damage checkpoint; negative regulation of transcription, DNA-templated; regulation of transcription, DNA-templated
Reference #:  D3ZIJ7 (UniProtKB)
Alt. Names/Synonyms: Checkpoint suppressor 1 (Predicted); Ches1; forkhead box N3; Foxn3; RGD1305711
Gene Symbols: Foxn3
Molecular weight: 50,365 Da
Basal Isoelectric point: 7.19  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  Pfam  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein