APOB48R Macrophage receptor that binds to the apolipoprotein B48 (APOB) of dietary triglyceride (TG)-rich lipoproteins (TRL) or to a like domain of APOB in hypertriglyceridemic very low density lipoprotein (HTG-VLDL). Binds and internalizes TRL when out of the context of the macrophage. May provide essential lipids to reticuloendothelial cells. Could also be involved in foam cell formation with elevated TRL and remnant lipoprotein (RLP). Mediates the rapid high-affinity uptake of chylomicrons (CM), HTG-VLDL, and trypsinized (tryp) VLDL devoid of APOE in vitro in macrophages. Expressed in peripheral blood leukocytes 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Receptor, misc.
Chromosomal Location of Human Ortholog: 1q36
Cellular Component: 
Molecular Function:  very-low-density lipoprotein particle receptor activity
Biological Process:  lipid transport; triglyceride metabolic process; vesicle-mediated transport
Reference #:  D4A7C9 (UniProtKB)
Alt. Names/Synonyms: APOB48R; Apobr; Apolipoprotein B receptor; RGD1565169
Gene Symbols: Apobr
Molecular weight: 86,313 Da
Basal Isoelectric point: 4.46  Predict pI for various phosphorylation states
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APOB48R

Protein Structure Not Found.

Cross-references to other databases:  Pfam  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein