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PYROXD1
Probable FAD-dependent oxidoreductase; involved in the cellular oxidative stress response. Required for normal sarcomere structure and muscle fiber integrity. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. PYROXD1 subfamily. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: EC 1.8.1.-; Oxidoreductase |
| Chromosomal Location of human Ortholog: 12p12.1 |
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Cellular Component:
nucleus; sarcomere
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Molecular Function:
flavin adenine dinucleotide binding; oxidoreductase activity; protein binding
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Biological Process:
cellular response to oxidative stress
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Disease: Myopathy, Myofibrillar, 8
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Reference #:
Q8WU10
(UniProtKB)
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Alt. Names/Synonyms: FLJ22028; MFM8; PYRD1; Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1; pyridine nucleotide-disulphide oxidoreductase domain 1; PYROXD1
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Gene Symbols: PYROXD1
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Molecular weight:
55,793 Da
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Basal Isoelectric point:
5.58
Predict pI for various phosphorylation states
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