|
FABP2
FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. Expressed in the small intestine and at much lower levels in the large intestine. Highest expression levels in the jejunum. Note: This description may include information from UniProtKB.
|
| Protein type: Lipid-binding; Transporter |
| Chromosomal Location of rat Ortholog: 2q42 |
|
Cellular Component:
apical cortex; cytoplasm; cytosol; microvillus; nucleus; plasma membrane
|
|
Molecular Function:
fatty acid binding; long-chain fatty acid binding; long-chain fatty acid transporter activity
|
|
Biological Process:
fatty acid metabolic process; fatty acid transport; intestinal absorption; intestinal lipid absorption; long-chain fatty acid transport
|
|
Reference #:
P02693
(UniProtKB)
|
|
Alt. Names/Synonyms: FABP2; Fatty acid-binding protein, intestinal
|
|
Gene Symbols: Fabp2
|
|
Molecular weight:
15,124 Da
|
|
Basal Isoelectric point:
6.63
Predict pI for various phosphorylation states
|
