ZNF136 May be involved in transcriptional regulation as a weak repressor when alone, or a potent one when fused with a heterologous protein containing a KRAB B-domain. Belongs to the krueppel C2H2-type zinc-finger protein family. Seems ubiquitous. Seen in the heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Note: This description may include information from UniProtKB.
Protein type: C2H2-type zinc finger protein; DNA-binding
Chromosomal Location of Human Ortholog: 19p13.2
Cellular Component:  nucleus
Molecular Function:  DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific; metal ion binding; protein binding; transcription corepressor activity
Biological Process:  negative regulation of transcription by RNA polymerase II; transcription by RNA polymerase II
Reference #:  P52737 (UniProtKB)
Alt. Names/Synonyms: pHZ-20; Zinc finger protein 136; ZN136; ZNF136
Gene Symbols: ZNF136
Molecular weight: 62,784 Da
Basal Isoelectric point: 9.32  Predict pI for various phosphorylation states
Select Structure to View Below

ZNF136

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene