AGA Cleaves the GlcNAc-Asn bond which joins oligosaccharides to the peptide of asparagine-linked glycoproteins. Belongs to the Ntn-hydrolase family. Note: This description may include information from UniProtKB.
Protein type: EC; Glycan Metabolism - other glycan degradation; Hydrolase
Chromosomal Location of Human Ortholog: 8|8 B1.3
Cellular Component:  cytoplasm; endoplasmic reticulum; extracellular space; lysosome
Molecular Function:  N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity; peptidase activity; protein self-association
Biological Process:  protein deglycosylation; proteolysis
Reference #:  Q64191 (UniProtKB)
Alt. Names/Synonyms: AGA; Aspartylglucosaminidase; ASPG; AW060726; Glycosylasparaginase; Glycosylasparaginase alpha chain; Glycosylasparaginase beta chain; N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase; N4-(N-acetyl-beta-glucosaminyl)-L-asparagine amidase
Gene Symbols: Aga
Molecular weight: 37,022 Da
Basal Isoelectric point: 5.99  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein