|
SYN2
Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. May play a role in noradrenaline secretion by sympathetic neurons. Belongs to the synapsin family. Central and peripheral nervous systems. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
|
| Protein type: Vesicle |
| Chromosomal Location of rat Ortholog: 4q42 |
|
Cellular Component:
anchoring junction; extrinsic component of synaptic vesicle membrane; glutamatergic synapse; plasma membrane; postsynaptic density; presynapse; Schaffer collateral - CA1 synapse; SNARE complex; synapse; synaptic vesicle; synaptic vesicle membrane
|
|
Molecular Function:
ATP binding; calcium-dependent protein binding; cytoskeletal protein binding; identical protein binding; protein binding
|
|
Biological Process:
calcium-ion regulated exocytosis; neurotransmitter secretion; regulation of neurotransmitter secretion; synaptic vesicle clustering; synaptic vesicle cycle
|
|
Reference #:
Q63537
(UniProtKB)
|
|
Alt. Names/Synonyms: Syn2; synapsin 2; Synapsin II; Synapsin-2
|
|
Gene Symbols: Syn2
|
|
Molecular weight:
63,457 Da
|
|
Basal Isoelectric point:
8.73
Predict pI for various phosphorylation states
|
|
CST Pathways:
GPCR Signaling to MAPKs
|
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
|
