PYGM Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. Belongs to the glycogen phosphorylase family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Carbohydrate Metabolism - starch and sucrose; EC; Endoplasmic reticulum; Phosphorylase; Transferase
Chromosomal Location of mouse Ortholog: 19 A|19 4.53 cM
Cellular Component:  cytoplasm; sarcoplasmic reticulum; Z disc
Molecular Function:  AMP binding; carbohydrate binding; catalytic activity; drug binding; glycogen phosphorylase activity; nucleotide binding; phosphorylase activity; pyridoxal phosphate binding; transferase activity; transferase activity, transferring glycosyl groups
Biological Process:  carbohydrate metabolic process; cellular calcium ion homeostasis; glycogen catabolic process; glycogen metabolic process; metabolic process; response to cAMP; response to hypoxia; response to organic substance
Reference #:  Q9WUB3 (UniProtKB)
Alt. Names/Synonyms: AI115133; Glycogen phosphorylase, muscle form; muscle glycogen phosphorylase; Myophosphorylase; OTTMUSP00000020157; Pygm
Gene Symbols: Pygm
Molecular weight: 97,286 Da
Basal Isoelectric point: 6.65  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  Reactome  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene