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PYGM
Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. Belongs to the glycogen phosphorylase family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Carbohydrate Metabolism - starch and sucrose; EC 2.4.1.1; Endoplasmic reticulum; Phosphorylase; Transferase |
| Chromosomal Location of mouse Ortholog: 19 A|19 4.53 cM |
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Cellular Component:
cytoplasm; sarcoplasmic reticulum; Z disc
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Molecular Function:
1,4-alpha-oligoglucan phosphorylase activity; AMP binding; carbohydrate binding; catalytic activity; glycogen phosphorylase activity; glycosyltransferase activity; linear malto-oligosaccharide phosphorylase activity; nucleotide binding; organic cyclic compound binding; pyridoxal phosphate binding; SHG alpha-glucan phosphorylase activity; transferase activity
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Biological Process:
carbohydrate metabolic process; glycogen catabolic process; glycogen metabolic process; intracellular calcium ion homeostasis; metabolic process; response to cAMP; response to hypoxia; response to organic substance
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Reference #:
Q9WUB3
(UniProtKB)
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Alt. Names/Synonyms: AI115133; Glycogen phosphorylase, muscle form; muscle glycogen phosphorylase; Myophosphorylase; OTTMUSP00000020157; Pygm
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Gene Symbols: Pygm
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Molecular weight:
97,286 Da
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Basal Isoelectric point:
6.65
Predict pI for various phosphorylation states
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