LRRC16B Belongs to the CARMIL family. Widely expressed, with much higher levels in fetal tissues than in adult ones. Up-regulated in certain cancer tissues. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Chromosomal Location of human Ortholog: 14q11.2
Cellular Component:  cytoplasm; lamellipodium; plasma membrane
Biological Process:  cell migration; regulation of actin cytoskeleton reorganization; regulation of Arp2/3 complex-mediated actin nucleation
Reference #:  Q8ND23 (UniProtKB)
Alt. Names/Synonyms: C14orf121; capping protein regulator and myosin 1 linker 3; Capping protein regulator and myosin 1 linker protein 3; Capping protein, Arp2/3 and myosin-I linker protein 3; CARL3; CARMIL3; crml-1; leucine rich repeat containing 16B; Leucine-rich repeat-containing protein 16B; LR16B; LRRC16B
Gene Symbols: CARMIL3
Molecular weight: 150,230 Da
Basal Isoelectric point: 7.2  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB