TCEA3 Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus. Belongs to the TFS-II family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Chromosomal Location of Human Ortholog: 5q36
Cellular Component:  nucleus
Molecular Function:  translation elongation factor activity; zinc ion binding
Biological Process:  regulation of transcription, DNA-templated; transcription, DNA-templated; translational elongation
Reference #:  Q5BK74 (UniProtKB)
Alt. Names/Synonyms: Tcea3; Transcription elongation factor A (SII), 3
Gene Symbols: Tcea3
Molecular weight: 38,978 Da
Basal Isoelectric point: 9.55  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  Pfam  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein