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MOSPD2
Promotes migration of primary monocytes and neutrophils, in response to various chemokines. Highly expressed in CD14(+) monocytes, and at lower levels in neutrophils. Does not show significant expression in B-cells or T-cells. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Membrane protein, integral |
| Chromosomal Location of rat Ortholog: Xq14 |
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Cellular Component:
endomembrane system; endoplasmic reticulum; endoplasmic reticulum-endosome membrane contact site; organelle membrane contact site; plasma membrane
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Biological Process:
positive regulation of monocyte chemotaxis; positive regulation of neutrophil chemotaxis
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Reference #:
D4A4X7
(UniProtKB)
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Alt. Names/Synonyms: Mospd2; motile sperm domain containing 2; Motile sperm domain-containing 2; RGD1563952
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Gene Symbols: Mospd2
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Molecular weight:
54,966 Da
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Basal Isoelectric point:
5.88
Predict pI for various phosphorylation states
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