UBC3B an E2 ubiquitin conjugating enzyme similar to UBC3/CDC34. Phosphorylation of UBC3B by CK2 induces its interaction with beta-TrCP, regulating beta-TrCP substrate recognition and enhancing beta-catenin degradation. Note: This description may include information from UniProtKB.
Protein type: EC 6.3.2.19; Ligase; Ubiquitin conjugating system; Ubiquitin ligase
Chromosomal Location of Human Ortholog: 9p13.3
Cellular Component:  cytosol
Molecular Function:  ATP binding; protein binding; ubiquitin conjugating enzyme activity; ubiquitin-protein transferase activity
Biological Process:  protein K48-linked ubiquitination; protein monoubiquitination; protein ubiquitination
Reference #:  Q712K3 (UniProtKB)
Alt. Names/Synonyms: CDC34B; E2-CDC34B; FLJ20419; MGC10481; UB2R2; UBC3B; UBE2R2; Ubiquitin carrier protein R2; Ubiquitin-conjugating enzyme E2 R2; Ubiquitin-conjugating enzyme E2-CDC34B; ubiquitin-conjugating enzyme E2R 2; ubiquitin-conjugating enzyme UBC3B; Ubiquitin-protein ligase R2
Gene Symbols: UBE2R2
Molecular weight: 27,166 Da
Basal Isoelectric point: 4.26  Predict pI for various phosphorylation states
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UBC3B

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene