FAM129B May play a role in apoptosis suppression. May promote melanoma cell invasion in vitro. Belongs to the Niban family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Cell adhesion
Chromosomal Location of Human Ortholog: 2|2 B
Cellular Component:  adherens junction; cell junction; cytoplasm; cytosol; membrane; nucleoplasm; plasma membrane
Molecular Function:  transcription coactivator activity
Biological Process:  gonadotropin secretion; negative regulation of apoptotic process; negative regulation of cell proliferation; negative regulation of DNA biosynthetic process; negative regulation of transcription, DNA-templated; positive regulation of transcription regulatory region DNA binding; positive regulation of transcription, DNA-templated
Reference #:  Q8R1F1 (UniProtKB)
Alt. Names/Synonyms: 9130404D14Rik; Fam129; Fam129b; family with sequence similarity 129, member B; Meg-3; NIBA2; niban apoptosis regulator 2; Niban-like protein 1; Niban2; NIBL1; OTTMUSP00000013425; Protein FAM129B; Protein Niban 2
Gene Symbols: Fam129b
Molecular weight: 84,819 Da
Basal Isoelectric point: 5.65  Predict pI for various phosphorylation states
Select Structure to View Below

FAM129B

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene