YTHDF2 high glucose-regulated protein 8. Two alternatively spliced isoforms have been described. Note: This description may include information from UniProtKB.
Protein type: RNA processing; RNA-binding
Chromosomal Location of Human Ortholog: 1p35.3
Cellular Component:  cytoplasmic ribonucleoprotein granule; cytosol; microtubule organizing center; nucleus; P-body
Molecular Function:  N6-methyladenosine-containing RNA binding; protein binding
Biological Process:  embryonic morphogenesis; endothelial to hematopoietic transition; humoral immune response; mRNA destabilization; negative regulation of Notch signaling pathway; oocyte maturation; positive regulation of cap-independent translational initiation; regulation of hematopoietic stem cell differentiation; regulation of meiotic cell cycle process involved in oocyte maturation; regulation of mRNA stability
Disease: Longevity 1
Reference #:  Q9Y5A9 (UniProtKB)
Alt. Names/Synonyms: 9430020E02Rik; CLL-associated antigen KW-14; HGR8; HGRG8; High-glucose-regulated protein 8; NY-REN-2; Renal carcinoma antigen NY-REN-2; YTH domain family protein 2; YTH domain family, member 2; YTH domain-containing family protein 2; YTHD2; YTHDF2
Gene Symbols: YTHDF2
Molecular weight: 62,334 Da
Basal Isoelectric point: 8.87  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein