CENPI Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Required for the localization of CENPF, MAD1L1 and MAD2 (MAD2L1 or MAD2L2) to kinetochores. Involved in the response of gonadal tissues to follicle-stimulating hormone. Belongs to the CENP-I/CTF3 family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: Xq22.1
Cellular Component:  cytosol; kinetochore; nuclear body; nucleoplasm
Molecular Function:  protein binding
Biological Process:  CENP-A containing nucleosome assembly; sex differentiation
Reference #:  Q92674 (UniProtKB)
Alt. Names/Synonyms: CENP-I; CENPI; Centromere protein I; Follicle-stimulating hormone primary response protein; FSH primary response 1; FSH primary response protein 1; FSHPRH1; ICEN19; Interphase centromere complex protein 19; Leucine-rich primary response protein 1; LRPR1; Mis6
Gene Symbols: CENPI
Molecular weight: 86,720 Da
Basal Isoelectric point: 8.98  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein