CENPI Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Required for the localization of CENPF, MAD1L1 and MAD2 (MAD2L1 or MAD2L2) to kinetochores. Involved in the response of gonadal tissues to follicle-stimulating hormone. Belongs to the CENP-I/CTF3 family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: Xq32
Cellular Component:  cytosol; kinetochore; nuclear body; nucleus
Biological Process:  centromere complex assembly; follicle-stimulating hormone signaling pathway
Reference #:  Q63517 (UniProtKB)
Alt. Names/Synonyms: CENP-I; Cenpi; Centromere protein I; Follicle stimulating hormone primary response gene 1 (Leucine - rich primary resonse gene 1); Follicle-stimulating hormone primary response protein; FSH primary response 1; FSH primary response protein 1; Fshprh1; Leucine-rich primary response protein 1; Lrpr1; RNALRP
Gene Symbols: Cenpi
Molecular weight: 85,651 Da
Basal Isoelectric point: 7.96  Predict pI for various phosphorylation states
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CENPI

Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene