PEAK1 Probable catalytically inactive kinase. Scaffolding protein that regulates the cytoskeleton to control cell spreading and migration by modulating focal adhesion dynamics. Acts as a scaffold for mediating EGFR signaling. Belongs to the protein kinase superfamily. Note: This description may include information from UniProtKB.
Protein type: EC 2.7.10.2; Kinase, protein; NKF3 family; Other group; Protein kinase, Other; Protein kinase, Ser/Thr (non-receptor)
Chromosomal Location of mouse Ortholog: 9|9 B
Cellular Component:  actin cytoskeleton; cell junction; cytoplasm; cytoskeleton; focal adhesion
Molecular Function:  ATP binding; identical protein binding; non-membrane spanning protein tyrosine kinase activity; protein kinase activity
Biological Process:  cell migration; focal adhesion assembly; protein autophosphorylation; protein phosphorylation; regulation of focal adhesion assembly; substrate adhesion-dependent cell spreading
Reference #:  Q69Z38 (UniProtKB)
Alt. Names/Synonyms: 1110049L02Rik; 9530046P14; AA690169; BE132841; C230081A13Rik; Inactive tyrosine-protein kinase PEAK1; Kiaa2002; mKIAA2002; NKF3 kinase family member; PEAK1; Pseudopodium-enriched atypical kinase 1; SG269; Sgk269; Sugen kinase 269; Tyrosine-protein kinase SgK269
Gene Symbols: Peak1
Molecular weight: 191,097 Da
Basal Isoelectric point: 6.45  Predict pI for various phosphorylation states
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PEAK1

Protein Structure Not Found.


Cross-references to other databases:  AlphaFold  |  STRING  |  BioGPS  |  KinBase  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene