TOM1L2 a protein of unknown function. Contains a VHS and GAT domain. The VHS domain is considered to have a general membrane targeting/cargo recognition role in vesicular trafficking. The GAT domain is responsible for binding of GGA proteins to several members of the ARF. It stabilizes membrane bound ARF1 in its GTP bound state, by interfering with GAP proteins. Note: This description may include information from UniProtKB.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 11|11 B2
Cellular Component: 
Molecular Function:  clathrin binding; protein kinase binding
Biological Process:  intracellular protein transport; negative regulation of mitotic nuclear division; protein transport; signal transduction
Reference #:  Q5SRX1 (UniProtKB)
Alt. Names/Synonyms: 2900016I08Rik; A730055F12Rik; AU042072; myb1-like protein 2; OTTMUSP00000005998; OTTMUSP00000005999; Srebf1; Target of Myb-like protein 2; target of myb1-like 2 (chicken); TM1L2; TOM1-like protein 2; Tom1l2
Gene Symbols: Tom1l2
Molecular weight: 55,663 Da
Basal Isoelectric point: 4.71  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene