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CENPI
Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Required for the localization of CENPF, MAD1L1 and MAD2 (MAD2L1 or MAD2L2) to kinetochores. Involved in the response of gonadal tissues to follicle-stimulating hormone. Belongs to the CENP-I/CTF3 family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Unknown function |
| Chromosomal Location of Human Ortholog: X|X E3 |
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Cellular Component:
chromosome; chromosome, centromeric region; cytosol; kinetochore; nuclear body; nucleus
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Biological Process:
centromere complex assembly
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Reference #:
Q8K1K4
(UniProtKB)
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Alt. Names/Synonyms: AI504163; CENP-I; Cenpi; Centromere protein I; Follicle-stimulating hormone primary response protein; FSH primary response 1; FSH primary response protein 1; Fshp; Fshprh1; MGC40943; OTTMUSP00000020775; OTTMUSP00000020776
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Gene Symbols: Cenpi
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Molecular weight:
85,403 Da
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Basal Isoelectric point:
8.33
Predict pI for various phosphorylation states
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