FAM98A Positively stimulates PRMT1-induced protein arginine methylation. Involved in skeletal homeostasis. Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts. Promotes colorectal cancer cell malignancy. Belongs to the FAM98 family. Expressed strongly in colorectal cancer cells (PubMed:28040436). Expressed strongly in colorectal cancer tissues compared to wild-type colon samples (at protein level) (PubMed:28040436). Expressed strongly in colorectal cancer tissues compared to wild-type colon samples (PubMed:28040436). Note: This description may include information from UniProtKB.
Protein type: RNA-binding
Chromosomal Location of Human Ortholog: 17|17 E2
Cellular Component:  tRNA-splicing ligase complex
Molecular Function:  protein binding; protein methyltransferase activity
Biological Process:  lysosome localization; positive regulation of cell proliferation; positive regulation of gene expression; positive regulation of ruffle assembly; protein methylation
Reference #:  Q3TJZ6 (UniProtKB)
Alt. Names/Synonyms: 2810405J04Rik; AL024114; FA98A; Fam98a; family with sequence similarity 98, member A; hypothetical protein LOC72722; Protein FAM98A
Gene Symbols: Fam98a
Molecular weight: 55,055 Da
Basal Isoelectric point: 9.09  Predict pI for various phosphorylation states
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FAM98A

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene