HDGF iso3 Heparin-binding protein, with mitogenic activity for fibroblasts. Acts as a transcriptional repressor. Belongs to the HDGF family. Ubiquitous. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Cytokine; Transcription regulation
Chromosomal Location of Human Ortholog: 1q23.1
Cellular Component:  cytoplasm; nucleoplasm; transcriptional repressor complex
Molecular Function:  DNA binding; growth factor activity; heparin binding; nucleotide binding; transcription corepressor activity; transcription corepressor binding
Biological Process:  cellular response to interleukin-7; IRE1-mediated unfolded protein response; negative regulation of transcription by RNA polymerase II; regulation of signaling receptor activity; signal transduction
Reference #:  P51858-3 (UniProtKB)
Alt. Names/Synonyms: epididymis secretory sperm binding protein; HDGF; HDGF iso3; heparin binding growth factor; hepatoma derived growth factor; Hepatoma-derived growth factor; High mobility group protein 1-like 2; HMG-1L2; HMG1L2
Gene Symbols: HDGF
Molecular weight: 28,264 Da
Basal Isoelectric point: 4.77  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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HDGF iso3

Protein Structure Not Found.


Cross-references to other databases:  cBioPortal  |  Wikipedia  |  Pfam  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein