SEPT2 a member of the septin family of proteins. May be involved in the process of cytokinesis. Accumulates near the contractile ring from anaphase through telophase, and finally condenses into the midbody. In interphase and postmitotic cells, localized to fibrous or granular structures, depending on the growth state of the cell. Note: This description may include information from UniProtKB.
Protein type: Cell cycle regulation; Cell development/differentiation; Cytoskeletal; Hydrolase; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 1|1 D
Cellular Component:  actin cytoskeleton; actomyosin contractile ring; axoneme; cell cortex; cell projection; cell surface; chromosome; chromosome, centromeric region; ciliary membrane; ciliary transition zone; cilium; cytoplasm; cytoskeleton; exocyst; kinetochore; membrane; microtubule cytoskeleton; midbody; motile cilium; non-motile cilium; nucleus; perinuclear region of cytoplasm; photoreceptor connecting cilium; plasma membrane; septin complex; septin ring; sperm annulus; spindle microtubule; synapse
Molecular Function:  enzyme regulator activity; GTP binding; GTPase activity; identical protein binding; molecular adaptor activity; nucleotide binding; protein binding
Biological Process:  cell cycle; cell differentiation; cell division; cilium assembly; cytoskeleton-dependent cytokinesis; neuron projection development; protein polymerization; regulation of L-glutamate import across plasma membrane; regulation of protein localization; smoothened signaling pathway; spermatogenesis
Reference #:  P42208 (UniProtKB)
Alt. Names/Synonyms: AW208991; mKIAA0158; NEDD-5; Nedd5; Neural precursor cell expressed developmentally down-regulated protein 5; neural precursor cell expressed, developmentally down-regulated gene 5; OTTMUSP00000024480; Sept2; septin 2; Septin-2
Gene Symbols: Sept2
Molecular weight: 41,526 Da
Basal Isoelectric point: 6.1  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene