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PRP4
Has a role in pre-mRNA splicing. Phosphorylates SF2/ASF. Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. Ubiquitous. Note: This description may include information from UniProtKB.
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| Protein type: CMGC group; DYRK family; EC 2.7.11.1; Kinase, protein; PRP4 subfamily; Protein kinase, CMGC; Protein kinase, Ser/Thr (non-receptor); RNA splicing; Spliceosome |
| Chromosomal Location of mouse Ortholog: 13|13 A3.3 |
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Cellular Component:
catalytic step 2 spliceosome; chromosome; nuclear speck; nucleus; spliceosomal complex
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Molecular Function:
ATP binding; kinase activity; nucleotide binding; protein kinase activity; protein serine/threonine kinase activity; transferase activity
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Biological Process:
mRNA cis splicing, via spliceosome; mRNA processing; phosphorylation; protein phosphorylation; RNA splicing
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Reference #:
Q61136
(UniProtKB)
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Alt. Names/Synonyms: 2610037H07; Cbp143; MGC5960; pre-mRNA processing factor 4B; Pre-mRNA protein kinase; Prp4; PRP4 pre-mRNA processing factor 4 homolog B; PRP4 pre-mRNA processing factor 4 homolog B (yeast); PRP4 pre-mRNA-processing factor 4 homolog; PRP4B; Prp4h; Prp4k; Prp4m; Prpf4b; Prpk; Serine/threonine-protein kinase PRP4 homolog
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Gene Symbols: Prpf4b
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Molecular weight:
116,976 Da
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Basal Isoelectric point:
10.23
Predict pI for various phosphorylation states
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