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EEF1A2
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. Brain, heart, and skeletal muscle. Note: This description may include information from UniProtKB.
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| Protein type: Translation; Translation elongation |
| Chromosomal Location of human Ortholog: 20q13.33 |
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Cellular Component:
cytoplasm; cytoplasmic side of lysosomal membrane; eukaryotic translation elongation factor 1 complex; nucleus; synapse
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Molecular Function:
GTP binding; GTPase activity; protein binding; protein kinase binding; translation elongation factor activity; translation factor activity, RNA binding
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Biological Process:
positive regulation of apoptotic process; positive regulation of lipid kinase activity; regulation of chaperone-mediated autophagy; translation; translational elongation
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Disease: Epileptic Encephalopathy, Early Infantile, 33; Mental Retardation, Autosomal Dominant 38
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Reference #:
Q05639
(UniProtKB)
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Alt. Names/Synonyms: eEF1A-2; EEF1A2; EEF1AL; EF-1-alpha-2; EF1A; EF1A2; EIEE33; Elongation factor 1-alpha 2; elongation factor-1 alpha; Eukaryotic elongation factor 1 A-2; eukaryotic translation elongation factor 1 alpha 2; FLJ41696; HS1; MRD38; statin S1; statin-like; Statin-S1; STN; STNL
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Gene Symbols: EEF1A2
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Molecular weight:
50,470 Da
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Basal Isoelectric point:
9.11
Predict pI for various phosphorylation states
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CST Pathways:
Translational Control
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