EEF1A2 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. Brain, heart, and skeletal muscle. Note: This description may include information from UniProtKB.
Protein type: Translation; Translation elongation
Chromosomal Location of Human Ortholog: 20q13.33
Cellular Component:  cytoplasm; cytoplasmic side of lysosomal membrane; eukaryotic translation elongation factor 1 complex; neuronal cell body; synapse
Molecular Function:  GTP binding; protein binding; protein kinase binding; translation factor activity, RNA binding
Biological Process:  positive regulation of apoptotic process; positive regulation of lipid kinase activity; regulation of chaperone-mediated autophagy; response to electrical stimulus; response to inorganic substance
Disease: Epileptic Encephalopathy, Early Infantile, 33; Mental Retardation, Autosomal Dominant 38
Reference #:  Q05639 (UniProtKB)
Alt. Names/Synonyms: eEF1A-2; EEF1A2; EEF1AL; EF-1-alpha-2; EF1A; EF1A2; EIEE33; Elongation factor 1-alpha 2; elongation factor-1 alpha; Eukaryotic elongation factor 1 A-2; eukaryotic translation elongation factor 1 alpha 2; FLJ41696; HS1; MRD38; statin S1; statin-like; Statin-S1; STN; STNL
Gene Symbols: EEF1A2
Molecular weight: 50,470 Da
Basal Isoelectric point: 9.11  Predict pI for various phosphorylation states
CST Pathways:  Translational Control
Select Structure to View Below

EEF1A2

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene