DDX3Y Probable ATP-dependent RNA helicase. May play a role in spermatogenesis. Belongs to the DEAD box helicase family. DDX3/DED1 subfamily. Testis-specific. Expressed predominantly in spermatogonia. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: EC; Helicase; RNA-binding
Chromosomal Location of Human Ortholog: Yq11.221
Cellular Component:  cytosol; nucleus
Molecular Function:  ATP binding; DNA binding; helicase activity; RNA binding
Disease: Spermatogenic Failure, Y-linked, 2
Reference #:  O15523 (UniProtKB)
Alt. Names/Synonyms: ATP-dependent RNA helicase DDX3Y; DBY; DDX3Y; DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked; DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked; DEAD box protein 3, Y-chromosomal; DEAD-box helicase 3 Y-linked; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide, Y chromosome
Gene Symbols: DDX3Y
Molecular weight: 73,154 Da
Basal Isoelectric point: 7.24  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB