SR-A1 May function in pre-mRNA splicing. Belongs to the splicing factor SR family. Ubiquitous. Highly expressed in fetal brain and liver, poorly expressed in salivary gland, heart, skin and ovary. Expressed in colorectal carcinomas and ovarian cancers. Overexpressed in colorectal carcinomas as compared to normal colonic mucosa. Note: This description may include information from UniProtKB.
Protein type: Unknown function
Chromosomal Location of human Ortholog: 19q13.33
Cellular Component:  nucleus
Molecular Function:  protein domain specific binding; RNA binding; RNA polymerase II C-terminal domain binding
Biological Process:  mRNA processing; RNA splicing; transcription by RNA polymerase II
Reference #:  Q9H7N4 (UniProtKB)
Alt. Names/Synonyms: FLJ00034; SCAF; SCAF1; Serine arginine-rich pre-mRNA splicing factor SR-A1; SFR19; SFRS19; Splicing factor, arginine/serine-rich 19; SR-A1; SR-related and CTD-associated factor 1; SR-related C-terminal domain-associated factor 1; SR-related CTD associated factor 1; SR-related CTD-associated factor 1; SR-related-CTD-associated factor; SRA1
Gene Symbols: SCAF1
Molecular weight: 139,270 Da
Basal Isoelectric point: 9.31  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene