LZP May be involved in hepatocellular function and development. Liver-specific. Expressed only in the hepatocytes. Down-regulated in hepatocellular carcinoma (HCC) and HCC cell lines. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Calcium-binding; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 10q22.1
Cellular Component:  nuclear envelope
Molecular Function:  calcium ion binding; protein binding
Biological Process:  urate homeostasis
Reference #:  Q8WWZ8 (UniProtKB)
Alt. Names/Synonyms: FLJ39116; Liver-specific zona pellucida domain-containing protein; liver-specific ZP domain-containing protein; LZP; OIT3; oncoprotein induced transcript 3; Oncoprotein-induced transcript 3 protein
Gene Symbols: OIT3
Molecular weight: 60,022 Da
Basal Isoelectric point: 5.34  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene