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LZP
May be involved in hepatocellular function and development. Liver-specific. Expressed only in the hepatocytes. Down-regulated in hepatocellular carcinoma (HCC) and HCC cell lines. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Calcium-binding; Secreted; Secreted, signal peptide |
| Chromosomal Location of human Ortholog: 10q22.1 |
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Cellular Component:
nuclear envelope
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Molecular Function:
calcium ion binding; protein binding
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Biological Process:
renal system process
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Reference #:
Q8WWZ8
(UniProtKB)
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Alt. Names/Synonyms: FLJ39116; Liver-specific zona pellucida domain-containing protein; liver-specific ZP domain-containing protein; LZP; OIT3; oncoprotein induced transcript 3; Oncoprotein-induced transcript 3 protein
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Gene Symbols: OIT3
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Molecular weight:
60,022 Da
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Basal Isoelectric point:
5.34
Predict pI for various phosphorylation states
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