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CADM4
Involved in the cell-cell adhesion. Has calcium- and magnesium-independent cell-cell adhesion activity. May have tumor-suppressor activity. Belongs to the nectin family. Expressed in brain, prostate, brain, kidney and some other organs. Note: This description may include information from UniProtKB.
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| Protein type: Cell adhesion; Membrane protein, integral; Tumor suppressor |
| Chromosomal Location of human Ortholog: 19q13.31 |
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Cellular Component:
cell leading edge; cell-cell contact zone; membrane
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Molecular Function:
protein phosphatase binding; receptor tyrosine kinase binding; vascular endothelial growth factor receptor 1 binding; vascular endothelial growth factor receptor 2 binding
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Biological Process:
homophilic cell adhesion via plasma membrane adhesion molecules; negative regulation of peptidyl-threonine phosphorylation; negative regulation of peptidyl-tyrosine phosphorylation; negative regulation of protein phosphorylation; negative regulation of vascular endothelial growth factor receptor signaling pathway; negative regulation of vascular endothelial growth factor signaling pathway; regulation of cell motility; regulation of cell population proliferation; regulation of protein phosphorylation; regulation of Rac protein signal transduction; regulation of wound healing
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Reference #:
Q8NFZ8
(UniProtKB)
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Alt. Names/Synonyms: CADM4; Cell adhesion molecule 4; IGSF4C; Immunoglobulin superfamily member 4C; immunoglobulin superfamily, member 4C; NECL-4; NECL4; nectin-like 4; Nectin-like protein 4; synCAM4; TSLC1-like 2; TSLC1-like protein 2; TSLL2
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Gene Symbols: CADM4
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Molecular weight:
42,785 Da
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Basal Isoelectric point:
5.92
Predict pI for various phosphorylation states
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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