STX2 Essential for epithelial morphogenesis. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm. Belongs to the syntaxin family. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Vesicle
Chromosomal Location of human Ortholog: 12q24.33
Cellular Component:  basolateral plasma membrane; extracellular space; intracellular membrane-bounded organelle; lamellipodium; plasma membrane
Molecular Function:  calcium-dependent protein binding; protein binding; protein dimerization activity
Biological Process:  acrosome reaction; animal organ morphogenesis; cell differentiation; cornified envelope assembly; ectoderm development; protein complex oligomerization; response to hydroperoxide; signal transduction
Reference #:  P32856 (UniProtKB)
Alt. Names/Synonyms: EPIM; Epimorphin; EPM; MGC51014; STX2; STX2A; STX2B; STX2C; syntaxin 2; Syntaxin-2
Gene Symbols: STX2
Molecular weight: 33,341 Da
Basal Isoelectric point: 5.92  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein