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STX2
Essential for epithelial morphogenesis. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm. Belongs to the syntaxin family. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Membrane protein, integral; Vesicle |
| Chromosomal Location of Human Ortholog: 12q24.33 |
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Cellular Component:
basolateral plasma membrane; extracellular space; intracellular membrane-bounded organelle; lamellipodium; plasma membrane
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Molecular Function:
calcium-dependent protein binding; protein binding; protein dimerization activity
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Biological Process:
acrosome reaction; animal organ morphogenesis; cell differentiation; cornified envelope assembly; ectoderm development; protein complex oligomerization; response to hydroperoxide; signal transduction
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Reference #:
P32856
(UniProtKB)
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Alt. Names/Synonyms: EPIM; Epimorphin; EPM; MGC51014; STX2; STX2A; STX2B; STX2C; syntaxin 2; Syntaxin-2
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Gene Symbols: STX2
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Molecular weight:
33,341 Da
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Basal Isoelectric point:
5.92
Predict pI for various phosphorylation states
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