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TRSPAP1
Involved in the early steps of selenocysteine biosynthesis and tRNA(Sec) charging to the later steps resulting in the cotranslational incorporation of selenocysteine into selenoproteins. Stabilizes the SECISBP2, EEFSEC and tRNA(Sec) complex. May be involved in the methylation of tRNA(Sec). Enhances efficiency of selenoproteins synthesis. Belongs to the RRM TRSPAP family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Chromosomal Location of human Ortholog: 1p35.3 |
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Cellular Component:
cytoplasm; nucleus
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Molecular Function:
protein binding; tRNA binding
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Biological Process:
selenocysteine incorporation
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Reference #:
Q9NX07
(UniProtKB)
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Alt. Names/Synonyms: FLJ20503; PRO1902; RP4-669K10.4; SECP43; tRNA selenocysteine 1 associated protein 1; tRNA selenocysteine 1-associated protein 1; tRNA selenocysteine associated protein (SECP43); tRNA selenocysteine associated protein 1; tRNA selenocysteine-associated protein 1; TRNAU1AP; TRSPAP1; TSAP1
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Gene Symbols: TRNAU1AP
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Molecular weight:
32,499 Da
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Basal Isoelectric point:
4.61
Predict pI for various phosphorylation states
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