E1B-AP5 Acts as a basic transcriptional regulator. Represses basic transcription driven by several virus and cellular promoters. When associated with BRD7, activates transcription of glucocorticoid-responsive promoter in the absence of ligand-stimulation. Plays also a role in mRNA processing and transport. Binds avidly to poly(G) and poly(C) RNA homopolymers in vitro. 5 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: RNA splicing; RNA-binding
Chromosomal Location of Human Ortholog: 7|7 A3
Cellular Component:  nucleoplasm; nucleus
Molecular Function:  enzyme binding; RNA binding
Biological Process:  response to virus; RNA processing
Reference #:  Q8VDM6 (UniProtKB)
Alt. Names/Synonyms: E130317O14Rik; E1B-A; E1B-AP5; E1BA; E1BAP5; EIB-55kDa associated protein 5; heterogeneous nuclear ribonucleoprotein U-like 1; Heterogeneous nuclear ribonucleoprotein U-like protein 1; Hnr; HNRL1; Hnrnpul; Hnrnpul1; Hnrpul1; MGC36621; MGC78330
Gene Symbols: Hnrnpul1
Molecular weight: 96,002 Da
Basal Isoelectric point: 6.18  Predict pI for various phosphorylation states
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E1B-AP5

Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene