Bright Transcription factor which may be involved in the control of cell cycle progression by the RB1/E2F1 pathway and in B-cell differentiation. Widely expressed, with highest expression in skeletal muscle, thalamus, and colon. Note: This description may include information from UniProtKB.
Protein type: Transcription factor
Chromosomal Location of mouse Ortholog: 10|10 C1
Cellular Component:  cytoplasm; cytosol; intracellular membrane-bounded organelle; membrane raft; nucleoplasm; nucleus
Molecular Function:  chromatin binding; DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor activity; protein binding; protein homodimerization activity; RNA polymerase II regulatory region sequence-specific DNA binding
Biological Process:  positive regulation of transcription by RNA polymerase II; regulation of transcription, DNA-templated
Reference #:  Q62431 (UniProtKB)
Alt. Names/Synonyms: ARI3A; ARID domain-containing protein 3A; Arid3a; AT rich interactive domain 3A (Bright like); AT rich interactive domain 3A (BRIGHT-like); AT-rich interactive domain-containing protein 3A; B-cell regulator of IgH transcription; Brig; Bright; dead ringer homolog 1; Dead ringer-like protein 1; Dri1; Dril1; OTTMUSP00000028002; OTTMUSP00000028004
Gene Symbols: Arid3a
Molecular weight: 64,173 Da
Basal Isoelectric point: 4.94  Predict pI for various phosphorylation states
Select Structure to View Below

Bright

Protein Structure Not Found.


Cross-references to other databases:  AlphaFold  |  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene