B-Myb Transcription factor involved in the regulation of cell survival, proliferation, and differentiation. Transactivates the expression of the CLU gene. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: DNA-binding; Motility/polarity/chemotaxis; Transcription factor
Chromosomal Location of Human Ortholog: 2 H2|2 84.0 cM
Cellular Component:  Myb complex; nucleoplasm; nucleus
Molecular Function:  DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II proximal promoter sequence-specific DNA binding
Biological Process:  cellular response to leukemia inhibitory factor; mitotic cell cycle; mitotic spindle assembly; positive regulation of neuron apoptotic process; positive regulation of transcription by RNA polymerase II; positive regulation of transcription, DNA-templated
Reference #:  P48972 (UniProtKB)
Alt. Names/Synonyms: B-Myb; Bmyb; Myb-like protein 2; Myb-related protein B; MYBB; Mybl2; myeloblastosis oncogene-like 2; OTTMUSP00000001107; RP23-335N12.7
Gene Symbols: Mybl2
Molecular weight: 79,103 Da
Basal Isoelectric point: 6.56  Predict pI for various phosphorylation states
Select Structure to View Below

B-Myb

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene